1.
Indian J Physiol Pharmacol
;
1981 Jul-Sep; 25(3): 269-73
Article
in English
| IMSEAR
| ID: sea-106206
ABSTRACT
Benzamido (alkyl) methyl pyrrolidine Mannich bases were synthetized and subjected to certain neuropharmacological studies. All the bases reduced the pentobarbitone sleeping time and rota-rod grip of rats. The Mannich bases II, III and V raised the minimal electro-shock seizure threshold of rats. The TAB-induced pyrexia was not reduced by the bases I and III in rabbits. None of the bases showed any significant analgesic activity.